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The best indicator for 3x Biotech Bull

We backtested 382 indicators across daily, weekly and hourly charts on real 3x Biotech Bull history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Mean Reversion · Daily

Fibonacci Pivots

On the daily chart, this is the strongest risk-adjusted edge we found for 3x Biotech Bull over ~11.1 years — beating buy-and-hold by 45.1% CAGR.

25.1%
CAGR
0.67
Sharpe
-71.6%
Max DD
53.4%
Win rate
1.16
Profit factor
+45.1%
vs Buy&Hold
Best by timeframe

The winner on each chart

Daily
Fibonacci Pivots
+45.1% · Sharpe 0.67
Weekly
Instantaneous Trendline
+36.9% · Sharpe 0.55
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1Fibonacci Pivots Daily25.1%0.67-71.6%53.4%48945.1%
2Pivot Points (Standard) Daily17.7%0.58-70.8%53.9%45137.7%
3Instantaneous Trendline Weekly16.6%0.55-70.7%29.2%2436.9%
4Laguerre RSI Daily15.5%0.54-76.3%65.0%8035.5%
5Connors RSI Weekly13.0%0.49-71.0%62.5%3233.3%
6Camarilla Pivots Daily10.4%0.48-75.5%50.2%61030.4%
7SSL Channel Daily8.3%0.44-84.2%43.9%11428.3%
8SMA 20/50 Cross Daily7.7%0.42-78.7%38.7%3127.7%
9Net Volume Daily7.2%0.42-83.2%43.3%12727.2%
10T3 10/40 Cross Daily7.9%0.42-88.3%42.4%3327.9%
11Liquidity Flow Oscillator Daily7.2%0.42-83.2%43.3%12727.2%
12Hull MA Trend Weekly7.7%0.42-70.6%46.4%2827.9%
13QQE Weekly1.4%0.42-97.7%39.4%3321.7%
14Demand Index Weekly2.7%0.42-94.7%58.8%3422.9%

= held up out-of-sample. Hypothetical, costs included. See methodology.

What this means

For 3x Biotech Bull, Fibonacci Pivots on the daily timeframe gave the best balance of return and risk in our test. It beat buy-and-hold — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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