13F holdings
PERCEPTIVE ADVISORS LLC portfolio
Managed by . 92 reported positions worth $5.1B as of 2026-03-31, filed with the SEC on 2026-05-29. This period was amended after its original filing; we use the latest document on file. Parsed from the filing itself, not a reseller.
$5.1B
Book value
92
Positions
52%
Top 10 weight
+18
New this quarter
-38
Exited
134 days
Age today
How old this actually is
Every position on this page is a snapshot of 2026-03-31. It was already 59 days old on 2026-05-29, the day it first became public. Today it is 134 days old.
That lag is the law, not a service level — Rule 13f-1 gives managers 45 days after quarter end to file, and no product can shorten it. A fund can have sold every share below before you read this sentence. Treat it as a record of what happened, never as a position you can follow.
What changed
Positions opened and closed
Against its 2025-12-31 filing. This is the part worth reading — the holdings table below is mostly years old.
New positions (18)
| Ticker | Issuer | Value | Shares | % of book |
|---|---|---|---|---|
| IONS | IONIS PHARMACEUTICALS INC | $37.8M | 504,000 | 0.75% |
| DAWNGBX | DAY ONE BIOPHARMACEUTICALS I | $37.6M | 1,755,799 | 0.74% |
| DAMORA THERAPEUTICS INC | DAMORA THERAPEUTICS INC | $31.7M | 1,223,000 | 0.63% |
| RVMD | REVOLUTION MEDICINES INC | $25.1M | 258,600 | 0.50% |
| DBVT | DBV TECHNOLOGIES S A | $20.1M | 964,391 | 0.40% |
| STRO | SUTRO BIOPHARMA INC | $17.8M | 715,307 | 0.35% |
| EVMN | EVOMMUNE INC | $10.3M | 448,350 | 0.20% |
| PHAT | PHATHOM PHARMACEUTICALS INC | $10.3M | 925,000 | 0.20% |
| NMRA | NEUMORA THERAPEUTICS INC. | $10.0M | 5,104,097 | 0.20% |
| TWST | TWIST BIOSCIENCE CORP | $7.1M | 150,000 | 0.14% |
| SRZN | SURROZEN INC | $6.7M | 229,393 | 0.13% |
| AGMB | AGOMAB THERAPEUTICS NV | $6.3M | 600,000 | 0.12% |
| EOLS | EVOLUS INC | $5.3M | 1,286,862 | 0.10% |
| APLSUSD | APELLIS PHARMACEUTICALS INC | $3.3M | 80,956 | 0.06% |
| EDSA | EDESA BIOTECH INC | $2.9M | 563,239 | 0.06% |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | $2.1M | 152,500 | 0.04% |
| CORT | CORCEPT THERAPEUTICS INC | $2.0M | 50,000 | 0.04% |
| XGN | EXAGEN INC | $344,679 | 114,893 | 0.01% |
Closed out (38)
| Ticker | Issuer | Was worth | Shares | % of book |
|---|---|---|---|---|
| EXK | EXACT SCIENCES CORP | $121.9M | 1,200,487 | 0.00% |
| ACLXGBX | ARCELLX INC | $95.6M | 1,466,071 | 0.00% |
| BSX | BOSTON SCIENTIFIC CORP | $93.3M | 979,000 | 0.00% |
| AM6 | AMICUS THERAPEUTICS INC | $90.7M | 6,370,851 | 0.00% |
| CATBUSD | ASTRIA THERAPEUTICS INC | $84.9M | 6,485,420 | 0.00% |
| DHR | DANAHER CORPORATION | $45.8M | 200,000 | 0.00% |
| CDTX | CIDARA THERAPEUTICS INC | $36.5M | 165,131 | 0.00% |
| IRON | DISC MEDICINE INC | $35.8M | 450,743 | 0.00% |
| PEN | PENUMBRA INC | $34.4M | 110,529 | 0.00% |
| CAI | CARIS LIFE SCIENCES INC | $30.7M | 1,136,206 | 0.00% |
| RAPT | RAPT THERAPEUTICS INC | $28.0M | 825,890 | 0.00% |
| PVLA | PALVELLA THERAPEUTICS INC NE | $27.9M | 266,287 | 0.00% |
| KOD | KODIAK SCIENCES INC | $23.7M | 848,900 | 0.00% |
| BIIB | BIOGEN INC | $21.8M | 124,000 | 0.00% |
| ALDX | ALDEYRA THERAPEUTICS INC | $21.7M | 4,185,632 | 0.00% |
| MIRM | MIRUM PHARMACEUTICALS INC | $20.5M | 259,545 | 0.00% |
| GRAL | GRAIL INC | $20.3M | 237,342 | 0.00% |
| CVS | CVS HEALTH CORP | $17.5M | 220,000 | 0.00% |
| GKOS | GLAUKOS CORP | $15.8M | 140,000 | 0.00% |
| DXCM | DEXCOM INC | $15.0M | 225,758 | 0.00% |
| SVRA | SAVARA INC | $14.5M | 2,400,000 | 0.00% |
| SEPN | SEPTERNA INC | $12.1M | 433,160 | 0.00% |
| GOSS | GOSSAMER BIO INC | $9.7M | 3,139,669 | 0.00% |
| MPLT | MAPLIGHT THERAPEUTICS INC | $9.7M | 550,000 | 0.00% |
| XENE | XENON PHARMACEUTICALS INC | $9.0M | 200,791 | 0.00% |
Added to (21)
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| PRAX | PRAXIS PRECISION MEDICINES I | $656.0M | 2,035,986 | 12.96% | +2% |
| ASCENDIS PHARMA A/S | ASCENDIS PHARMA A/S | $350.3M | 1,531,421 | 6.92% | +42% |
| ROIV | ROIVANT SCIENCES LTD | $229.5M | 8,285,461 | 4.53% | +4% |
| 260 | CENTESSA PHARMACEUTICALS PLC | $208.9M | 5,258,903 | 4.13% | +80% |
| SYRE | SPYRE THERAPEUTICS INC | $190.8M | 3,783,225 | 3.77% | +23% |
| RLAY | RELAY THERAPEUTICS INC | $97.0M | 9,751,141 | 1.92% | +412% |
| ZYME | ZYMEWORKS INC | $87.9M | 3,510,078 | 1.74% | +8% |
| DYN | DYNE THERAPEUTICS INC | $84.6M | 4,668,839 | 1.67% | +34% |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $70.8M | 7,434,033 | 1.40% | +135% |
| NRIX | NURIX THERAPEUTICS INC | $57.5M | 3,710,877 | 1.14% | +4% |
| CTMX | CYTOMX THERAPEUTICS INC. | $47.5M | 10,098,824 | 0.94% | +4% |
| ANRO | ALTO NEUROSCIENCE INC | $45.2M | 2,009,893 | 0.89% | +13% |
| CRVS | CORVUS PHARMACEUTICALS INC | $33.5M | 2,292,441 | 0.66% | +231% |
| XFOR | X4 PHARMACEUTICALS INC | $27.8M | 6,737,648 | 0.55% | +7% |
| GH | GUARDANT HEALTH INC | $27.7M | 300,000 | 0.55% | +88% |
Trimmed (30)
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| NBIX | NEUROCRINE BIOSCIENCES INC | $8.6M | 65,050 | 0.17% | -80% |
| OMDA | OMADA HEALTH INC | $9.9M | 786,330 | 0.20% | -67% |
| BLTE | BELITE BIO INC | $24.2M | 151,979 | 0.48% | -63% |
| VRDN | VIRIDIAN THERAPEUTICS INC | $22.9M | 1,170,829 | 0.45% | -62% |
| IRD | OPUS GENETICS INC | $8.4M | 1,835,842 | 0.16% | -58% |
| IKT | INHIBIKASE THERAPEUTICS INC | $3.9M | 2,315,000 | 0.08% | -57% |
| CBIO | CRESCENT BIOPHARMA INC. | $3.8M | 206,942 | 0.08% | -54% |
| ADMA | ADMA BIOLOGICS INC | $4.2M | 467,233 | 0.08% | -47% |
| SION | SIONNA THERAPEUTICS INC | $26.4M | 658,439 | 0.52% | -44% |
| CPIX | CUMBERLAND PHARMACEUTICALS I | $640,179 | 196,978 | 0.01% | -42% |
| APGE | APOGEE THERAPEUTICS INC | $129.7M | 1,540,384 | 2.56% | -34% |
| ABVX | ABIVAX SA | $36.6M | 328,884 | 0.72% | -28% |
| PALI | PALISADE BIO INC | $15.6M | 8,928,149 | 0.31% | -26% |
| IMVT | IMMUNOVANT INC | $39.7M | 1,597,383 | 0.78% | -20% |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | $27.5M | 377,544 | 0.54% | -16% |
The book
All reported holdings
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| PRAX | PRAXIS PRECISION MEDICINES I | $656.0M | 2,035,986 | 12.96% | — |
| CELC | CELCUITY INC | $356.9M | 3,127,200 | 7.05% | — |
| ASCENDIS PHARMA A/S | ASCENDIS PHARMA A/S | $350.3M | 1,531,421 | 6.92% | — |
| ROIV | ROIVANT SCIENCES LTD | $229.5M | 8,285,461 | 4.53% | — |
| 260 | CENTESSA PHARMACEUTICALS PLC | $208.9M | 5,258,903 | 4.13% | — |
| RYTM | RHYTHM PHARMACEUTICALS INC | $206.4M | 2,373,795 | 4.08% | — |
| SYRE | SPYRE THERAPEUTICS INC | $190.8M | 3,783,225 | 3.77% | — |
| NUVALENT INC | NUVALENT INC | $161.9M | 1,580,505 | 3.20% | — |
| EWTX | EDGEWISE THERAPEUTICS INC | $139.4M | 4,423,974 | 2.75% | — |
| PTGX | PROTAGONIST THERAPEUTICS INC | $129.7M | 1,230,879 | 2.56% | — |
| APGE | APOGEE THERAPEUTICS INC | $129.7M | 1,540,384 | 2.56% | — |
| TVTX | TRAVERE THERAPEUTICS INC | $123.1M | 4,142,551 | 2.43% | — |
| AMLX | AMYLYX PHARMACEUTICALS INC | $115.2M | 8,284,882 | 2.27% | — |
| IMMATICS N.V | IMMATICS N.V | $102.2M | 10,383,456 | 2.02% | — |
| RLAY | RELAY THERAPEUTICS INC | $97.0M | 9,751,141 | 1.92% | — |
| INBX | INHIBRX BIOSCIENCES INC | $97.0M | 1,442,707 | 1.92% | — |
| MGTX | MEIRAGTX HLDGS PLC | $89.3M | 10,326,103 | 1.76% | — |
| ZYME | ZYMEWORKS INC | $87.9M | 3,510,078 | 1.74% | — |
| SLDB | SOLID BIOSCIENCES INC | $85.7M | 11,906,646 | 1.69% | — |
| DYN | DYNE THERAPEUTICS INC | $84.6M | 4,668,839 | 1.67% | — |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $70.8M | 7,434,033 | 1.40% | — |
| ORKA | ORUKA THERAPEUTICS INC | $68.4M | 1,395,501 | 1.35% | — |
| AORT | ARTIVION INC | $60.0M | 1,637,290 | 1.18% | — |
| NRIX | NURIX THERAPEUTICS INC | $57.5M | 3,710,877 | 1.14% | — |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | $48.9M | 12,594,211 | 0.97% | — |
| CTMX | CYTOMX THERAPEUTICS INC. | $47.5M | 10,098,824 | 0.94% | — |
| ANRO | ALTO NEUROSCIENCE INC | $45.2M | 2,009,893 | 0.89% | — |
| ENGENE HOLDINGS INC | ENGENE HOLDINGS INC | $39.7M | 5,827,506 | 0.78% | — |
| IMVT | IMMUNOVANT INC | $39.7M | 1,597,383 | 0.78% | — |
| ISRG | INTUITIVE SURGICAL INC | $39.4M | 85,419 | 0.78% | — |
| IONS | IONIS PHARMACEUTICALS INC | $37.8M | 504,000 | 0.75% | — |
| DAWNGBX | DAY ONE BIOPHARMACEUTICALS I | $37.6M | 1,755,799 | 0.74% | — |
| ABVX | ABIVAX SA | $36.6M | 328,884 | 0.72% | — |
| CRVS | CORVUS PHARMACEUTICALS INC | $33.5M | 2,292,441 | 0.66% | — |
| RGEN | REPLIGEN CORP | $33.1M | 280,541 | 0.65% | — |
| JAZZ | JAZZ PHARMACEUTICALS PLC | $32.1M | 170,000 | 0.63% | — |
| DAMORA THERAPEUTICS INC | DAMORA THERAPEUTICS INC | $31.7M | 1,223,000 | 0.63% | — |
| XFOR | X4 PHARMACEUTICALS INC | $27.8M | 6,737,648 | 0.55% | — |
| GH | GUARDANT HEALTH INC | $27.7M | 300,000 | 0.55% | — |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | $27.5M | 377,544 | 0.54% | — |
| IVVD | INVIVYD INC | $27.1M | 20,859,303 | 0.54% | — |
| SION | SIONNA THERAPEUTICS INC | $26.4M | 658,439 | 0.52% | — |
| AXSM | AXSOME THERAPEUTICS INC. | $25.3M | 149,950 | 0.50% | — |
| RVMD | REVOLUTION MEDICINES INC | $25.1M | 258,600 | 0.50% | — |
| SABS | SAB BIOTHERAPEUTICS INC | $24.6M | 6,431,743 | 0.49% | — |
| BLTE | BELITE BIO INC | $24.2M | 151,979 | 0.48% | — |
| TENX | TENAX THERAPEUTICS INC | $23.2M | 1,447,782 | 0.46% | — |
| AXGN | AXOGEN INC | $23.1M | 697,312 | 0.46% | — |
| VRDN | VIRIDIAN THERAPEUTICS INC | $22.9M | 1,170,829 | 0.45% | — |
| OBIO | ORCHESTRA BIOMED HLDGS INC | $21.4M | 5,037,906 | 0.42% | — |
| RAPP | RAPPORT THERAPEUTICS INC | $21.1M | 673,923 | 0.42% | — |
| DBVT | DBV TECHNOLOGIES S A | $20.1M | 964,391 | 0.40% | — |
| LONA | LEONABIO INC | $19.1M | 1,859,322 | 0.38% | — |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | $19.0M | 3,425,476 | 0.38% | — |
| STRO | SUTRO BIOPHARMA INC | $17.8M | 715,307 | 0.35% | — |
| TNGX | TANGO THERAPEUTICS INC | $16.9M | 808,153 | 0.33% | — |
| CTNM | CONTINEUM THERAPEUTICS INC | $16.4M | 1,255,592 | 0.32% | — |
| CELC 2.75 08/01/31 | CELCUITY INC | $15.9M | 6,500,000 | 0.31% | — |
| PALI | PALISADE BIO INC | $15.6M | 8,928,149 | 0.31% | — |
| OCS | OCULIS HOLDING AG | $13.1M | 493,827 | 0.26% | — |
| IRTC | IRHYTHM HOLDINGS INC | $12.4M | 105,026 | 0.24% | — |
| ADGM | ADAGIO MED HLDGS INC | $11.0M | 9,876,576 | 0.22% | — |
| EVMN | EVOMMUNE INC | $10.3M | 448,350 | 0.20% | — |
| PHAT | PHATHOM PHARMACEUTICALS INC | $10.3M | 925,000 | 0.20% | — |
| NMRA | NEUMORA THERAPEUTICS INC. | $10.0M | 5,104,097 | 0.20% | — |
| OMDA | OMADA HEALTH INC | $9.9M | 786,330 | 0.20% | — |
| NBIX | NEUROCRINE BIOSCIENCES INC | $8.6M | 65,050 | 0.17% | — |
| BBNX | BETA BIONICS INC | $8.4M | 842,944 | 0.17% | — |
| IRD | OPUS GENETICS INC | $8.4M | 1,835,842 | 0.16% | — |
| BLLN | BILLIONTOONE INC | $7.2M | 91,812 | 0.14% | — |
| TWST | TWIST BIOSCIENCE CORP | $7.1M | 150,000 | 0.14% | — |
| SRZN | SURROZEN INC | $6.7M | 229,393 | 0.13% | — |
| AGMB | AGOMAB THERAPEUTICS NV | $6.3M | 600,000 | 0.12% | — |
| EOLS | EVOLUS INC | $5.3M | 1,286,862 | 0.10% | — |
| COGT | COGENT BIOSCIENCES INC | $4.7M | 121,082 | 0.09% | — |
| ADMA | ADMA BIOLOGICS INC | $4.2M | 467,233 | 0.08% | — |
| IKT | INHIBIKASE THERAPEUTICS INC | $3.9M | 2,315,000 | 0.08% | — |
| CBIO | CRESCENT BIOPHARMA INC. | $3.8M | 206,942 | 0.08% | — |
| APLSUSD | APELLIS PHARMACEUTICALS INC | $3.3M | 80,956 | 0.06% | — |
| OM | OUTSET MED INC | $3.2M | 833,333 | 0.06% | — |
| EDSA | EDESA BIOTECH INC | $2.9M | 563,239 | 0.06% | — |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | $2.1M | 152,500 | 0.04% | — |
| AVTX | AVALO THERAPEUTICS INC | $2.1M | 139,667 | 0.04% | — |
| CNTB | CONNECT BIOPHARMA HLDGS LTD | $2.1M | 792,696 | 0.04% | — |
| CORT | CORCEPT THERAPEUTICS INC | $2.0M | 50,000 | 0.04% | — |
| MDLN | MEDLINE INC | $1.2M | 28,000 | 0.02% | — |
| PTN | PALATIN TECHNOLOGIES INC | $1.1M | 61,945 | 0.02% | — |
| CPIX | CUMBERLAND PHARMACEUTICALS I | $640,179 | 196,978 | 0.01% | — |
| RVMDW | REVOLUTION MEDICINES INC | $447,500 | 250,000 | 0.01% | — |
| XGN | EXAGEN INC | $344,679 | 114,893 | 0.01% | — |
| ENSC | ENSYSCE BIOSCIENCES INC | $46,670 | 86,666 | 0.00% | — |
| SURROZEN INC | SURROZEN INC | $2,667 | 166,666 | 0.00% | — |
This manager also disclosed 2 options positions with a combined notional of $55.0M. Notional is not ownership, so it is excluded from the book value above rather than folded in to make the fund look bigger.
Rows are aggregated by CUSIP — a manager files the same security multiple times when different internal desks hold it. Tickers link to our own backtest of that asset where we cover it.
Read the original
This page was built from one document: the 2026-03-31 Form 13F info table filed by PERCEPTIVE ADVISORS LLC (CIK 1224962, accession 0001012975-26-000499). Every other 13F site is reading the same file.
If anything here disagrees with it, the filing wins — and we would want to know. All 13F filings by this manager
What a 13F cannot show you
A 13F is a long-only equity snapshot, and the holes in it are structural. Anyone selling you this data as "what the smart money is doing" is selling you one leg of a position:
- No short positions. None, ever. A fund shown here as bullish may be net short the same name through a book you cannot see.
- No cash, bonds, FX, commodities or non-US listings. A macro fund's entire thesis can be invisible.
- No intra-quarter round trips. Bought and sold inside the same quarter means it never appears at all.
- Options are notional, not ownership. We keep puts and calls in a separate bucket rather than adding their notional into a fund's book size, which is how a $2B fund gets reported as a $20B one.
- Confidential treatment. Managers can ask the SEC to withhold a position while they build it. Those holdings are legally absent from the filing, so a "new" position may be months old.
Tested and published by IndicatorEdge · backtest grid generated 2026-06-25 · base rates recomputed 2026-07-31 · how we test
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