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The best indicator for Intuitive Surgical (ISRG)

We backtested 366 indicators across daily, weekly and hourly charts on real Intuitive Surgical (ISRG) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Signaling FLAT right now — Hull MA 20/80 Cross (Weekly) is out of the market, as of 2026-06-08.
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Trend · Weekly

Hull MA 20/80 Cross

On the weekly chart, this is the strongest risk-adjusted edge we found for Intuitive Surgical (ISRG) over ~26.1 years — trailing buy-and-hold by 1.9% CAGR.

20.8%
CAGR
0.81
Sharpe
-36.3%
Max DD
66.7%
Win rate
7.81
Profit factor
-1.9%
vs Buy&Hold
Confluence · Weekly

Best multi-indicator combo

StochasticFisher Transform

Going long only when all 2 agree was the strongest confluence setup we found for Intuitive Surgical (ISRG) — trailing buy-and-hold by 19.3% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.

3.4%
CAGR
0.26
Sharpe
44.6%
Win rate
56
Trades
-19.3%
vs Buy&Hold
Best by timeframe

The winner on each chart

Weekly
Hull MA 20/80 Cross
-1.9% · Sharpe 0.81
Daily
FRAMA 10/30 Cross
-2.3% · Sharpe 0.75
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1Hull MA 20/80 Cross Weekly20.8%0.81-36.3%66.7%27-1.9%
2SMA 20/50 Cross Weekly22.6%0.79-40.9%80.0%15-0.1%
3T3 8/21 Cross Weekly19.9%0.78-46.8%65.0%20-2.8%
4DEMA 20/50 Cross Weekly20.4%0.77-33.5%57.9%19-2.3%
5TEMA 20/50 Cross Weekly19.3%0.77-36.9%70.0%30-3.4%
6FRAMA 10/30 Cross Daily20.6%0.75-41.6%53.1%473-2.3%
7LSMA 10/30 Cross Daily20.1%0.72-53.6%49.1%275-2.8%
8Ehlers Roofing Filter Weekly18.9%0.72-56.2%69.6%23-3.9%
9Parabolic SAR Daily20.5%0.71-59.6%47.9%282-2.4%
10ALMA 200 Trend Weekly18.0%0.71-44.8%50.0%20-4.7%
11ZLEMA 100 Trend Weekly16.9%0.71-38.6%56.8%44-5.8%
12LSMA 200 Trend Weekly16.3%0.7-39.4%55.9%34-6.4%
13DEMA 200 Trend Daily16.4%0.69-48.7%43.3%127-6.5%
14T3 20/80 Cross Daily16.9%0.69-50.9%44.4%36-6.0%

= held up out-of-sample. Hypothetical, costs included. See methodology.

What this means

For Intuitive Surgical (ISRG), Hull MA 20/80 Cross on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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