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The best indicator for Intuitive Surgical (ISRG)

We backtested 382 indicators across daily, weekly and hourly charts on real Intuitive Surgical (ISRG) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Signaling FLAT right now — Hull MA 20/80 Cross (Weekly) is out of the market. Signal computed on 2026-09-07, 2 days behind the price data on this page (it is rebuilt on a separate schedule).
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Key levels · as of 2026-09-09

Where Intuitive Surgical (ISRG) stands

353.24
last daily close (2026-09-09)
461.77
200-day simple moving average price 23.5% below
378.87
50-day simple moving average price 6.8% below
332.02–592.85
52-week range

Computed from our own daily OHLCV history, not quoted from a third party. Moving averages use closing prices; "52-week" is the last 252 trading sessions.

Trend · Weekly

Hull MA 20/80 Cross

On the weekly chart, this is the strongest risk-adjusted edge we found for Intuitive Surgical (ISRG) over ~26.1 years — trailing buy-and-hold by 1.9% CAGR.

20.8%
CAGR
0.81
Sharpe
-36.3%
Max DD
66.7%
Win rate
7.81
Profit factor
-1.9%
vs Buy&Hold
Chart

Intuitive Surgical (ISRG) on the weekly chart

The timeframe our backtest found best for this asset. The chart is live market data; the results above are hypothetical and historical.

Chart by TradingView. Loading it contacts tradingview.com, which may set its own cookies — see our privacy policy.

NOTHING BEAT BUY-AND-HOLD
Full strategy report — every setup ranked out-of-sample, corrected for data-mining, and forward-tracked in public.
Read the verdict
Confluence · Weekly

Best multi-indicator combo

StochasticFisher Transform

Going long only when all 2 agree was the strongest confluence setup we found for Intuitive Surgical (ISRG) — trailing buy-and-hold by 19.3% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.

3.4%
CAGR
0.26
Sharpe
44.6%
Win rate
56
Trades
-19.3%
vs Buy&Hold
Best by timeframe

The winner on each chart

Weekly
Hull MA 20/80 Cross
-1.9% · Sharpe 0.81
Daily
FRAMA 10/30 Cross
-2.3% · Sharpe 0.75
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1Hull MA 20/80 Cross Weekly20.8%0.81-36.3%66.7%27-1.9%
2SMA 20/50 Cross Weekly22.6%0.79-40.9%80.0%15-0.1%
3T3 8/21 Cross Weekly19.9%0.78-46.8%65.0%20-2.8%
4DEMA 20/50 Cross Weekly20.4%0.77-33.5%57.9%19-2.3%
5TEMA 20/50 Cross Weekly19.3%0.77-36.9%70.0%30-3.4%
6FRAMA 10/30 Cross Daily20.6%0.75-41.6%53.1%473-2.3%
7LSMA 10/30 Cross Daily20.1%0.72-53.6%49.1%275-2.8%
8Ehlers Roofing Filter Weekly18.9%0.72-56.2%69.6%23-3.9%
9Parabolic SAR Daily20.5%0.71-59.6%47.9%282-2.4%
10ALMA 200 Trend Weekly18.0%0.71-44.8%50.0%20-4.7%
11ZLEMA 100 Trend Weekly16.9%0.71-38.6%56.8%44-5.8%
12LSMA 200 Trend Weekly16.3%0.7-39.4%55.9%34-6.4%
13DEMA 200 Trend Daily16.4%0.69-48.7%43.3%127-6.5%
14T3 20/80 Cross Daily16.9%0.69-50.9%44.4%36-6.0%

= held up out-of-sample. Hypothetical, costs included. See methodology.

The leverage question

What it would take to beat buy & hold on Intuitive Surgical (ISRG)

18 of 671 tested setups beat buy-and-hold on Intuitive Surgical (ISRG) outright. Another 271 could get there with leverage they would survive — but 232 would be liquidated by their own drawdown before they caught it.

IndicatorBeats B&H unlevered Leverage neededLeverage survived
ADXR11.13×3.87×
Connors RSI-211.36×3.57×
DMI Direction11.6×3.05×
QQE11.85×2.3×
Connors RSI12.5×3.1×
DEMA 20/50 Cross1none needed2.76×

Out-of-sample, costs included. A setup is only listed if the leverage it needs is less than the leverage its own worst drawdown survives — when it isn't, no amount of leverage gets there. Volatility drag isn't modelled, so these are the optimistic case. Every indicator, ranked this way

What this means

For Intuitive Surgical (ISRG), Hull MA 20/80 Cross on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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