13F holdings
DEERFIELD MANAGEMENT COMPANY, L.P. portfolio
Managed by . 82 reported positions worth $8.5B as of 2026-03-31, filed with the SEC on 2026-05-15. Parsed from the filing itself, not a reseller.
$8.5B
Book value
82
Positions
51%
Top 10 weight
+12
New this quarter
-79
Exited
134 days
Age today
How old this actually is
Every position on this page is a snapshot of 2026-03-31. It was already 45 days old on 2026-05-15, the day it first became public. Today it is 134 days old.
That lag is the law, not a service level — Rule 13f-1 gives managers 45 days after quarter end to file, and no product can shorten it. A fund can have sold every share below before you read this sentence. Treat it as a record of what happened, never as a position you can follow.
What changed
Positions opened and closed
Against its 2025-12-31 filing. This is the part worth reading — the holdings table below is mostly years old.
New positions (12)
| Ticker | Issuer | Value | Shares | % of book |
|---|---|---|---|---|
| ARWR 0 01/15/32 | ARROWHEAD PHARMACEUTICALS IN | $207.2M | 200,000,000 | 2.44% |
| INDV | INDIVIOR PHARMACEUTICALS INC | $94.4M | 3,097,790 | 1.11% |
| SNDX | SYNDAX PHARMACEUTICALS INC | $88.3M | 3,779,900 | 1.04% |
| DNTH | DIANTHUS THERAPEUTICS INC | $85.6M | 1,019,813 | 1.01% |
| PFE | PFIZER INC | $85.4M | 3,040,000 | 1.01% |
| ZBIO 2.5 04/01/32 | ZENAS BIOPHARMA INC | $67.3M | 65,000,000 | 0.79% |
| GMAB | GENMAB A/S | $66.1M | 2,462,000 | 0.78% |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $48.1M | 851,556 | 0.57% |
| TYRA | TYRA BIOSCIENCES INC | $21.0M | 549,000 | 0.25% |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | $20.7M | 283,000 | 0.24% |
| SGP | SPYGLASS PHARMA INC | $14.3M | 550,000 | 0.17% |
| MANE | VERADERMICS INC | $315,750 | 5,000 | 0.00% |
Closed out (79)
| Ticker | Issuer | Was worth | Shares | % of book |
|---|---|---|---|---|
| INDV | INDIVIOR PLC | $121.7M | 3,393,063 | 0.00% |
| PHR | PHREESIA INC | $33.8M | 1,999,045 | 0.00% |
| LNTH 2.625 12/15/27 | LANTHEUS HLDGS INC | $28.9M | 25,255,000 | 0.00% |
| VTR | VENTAS INC | $27.4M | 354,000 | 0.00% |
| SYRE | SPYRE THERAPEUTICS INC | $23.3M | 710,626 | 0.00% |
| EWTX | EDGEWISE THERAPEUTICS INC | $19.0M | 765,694 | 0.00% |
| CRMD | CORMEDIX INC | $12.9M | 1,107,944 | 0.00% |
| MDLN | MEDLINE INC | $10.9M | 260,000 | 0.00% |
| OMDA | OMADA HEALTH INC | $8.7M | 553,107 | 0.00% |
| CALC | CALCIMEDICA INC | $8.6M | 1,300,000 | 0.00% |
| PBH | PRESTIGE CONSMR HEALTHCARE I | $4.3M | 69,669 | 0.00% |
| VEEV | VEEVA SYS INC | $4.0M | 17,711 | 0.00% |
| RDNT | RADNET INC | $3.6M | 49,951 | 0.00% |
| LH | LABCORP HOLDINGS INC | $3.5M | 13,825 | 0.00% |
| ENOV | ENOVIS CORPORATION | $3.4M | 127,270 | 0.00% |
| ALHC | ALIGNMENT HEALTHCARE INC | $3.2M | 164,345 | 0.00% |
| DGX | QUEST DIAGNOSTICS INC | $3.2M | 18,392 | 0.00% |
| TMDX | TRANSMEDICS GROUP INC | $3.1M | 25,492 | 0.00% |
| PODD | INSULET CORP | $3.0M | 10,616 | 0.00% |
| BLFS | BIOLIFE SOLUTIONS INC | $2.9M | 120,211 | 0.00% |
| CHE | CHEMED CORP NEW | $2.7M | 6,215 | 0.00% |
| WOOF | PETCO HEALTH & WELLNESS CO I | $2.6M | 936,309 | 0.00% |
| KIDS | ORTHOPEDIATRICS CORP | $2.6M | 144,220 | 0.00% |
| CI | THE CIGNA GROUP | $2.5M | 9,203 | 0.00% |
| TRUP | TRUPANION INC | $2.5M | 66,438 | 0.00% |
Added to (14)
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| PRAX | PRAXIS PRECISION MEDICINES I | $310.4M | 963,351 | 3.66% | +7% |
| UTHR | UNITED THERAPEUTICS CORP DEL | $271.0M | 457,000 | 3.20% | +7% |
| LRMR | LARIMAR THERAPEUTICS INC | $160.2M | 35,606,974 | 1.89% | +16% |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $143.2M | 15,038,000 | 1.69% | +5% |
| INSP | INSPIRE MED SYS INC | $139.4M | 2,703,238 | 1.64% | +80% |
| LEGN | LEGEND BIOTECH CORP | $139.1M | 7,687,638 | 1.64% | +30% |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | $136.5M | 4,264,789 | 1.61% | +2% |
| XENE | XENON PHARMACEUTICALS INC | $94.0M | 1,615,696 | 1.11% | +198% |
| TNGX | TANGO THERAPEUTICS INC | $86.8M | 4,146,813 | 1.02% | +43% |
| BLTE | BELITE BIO INC | $48.5M | 304,013 | 0.57% | +30% |
| IRON | DISC MEDICINE INC | $42.0M | 657,000 | 0.50% | +29% |
| FHTX | FOGHORN THERAPEUTICS INC | $21.0M | 4,394,367 | 0.25% | +20% |
| MNPR | MONOPAR THERAPEUTICS INC | $17.7M | 323,745 | 0.21% | +90% |
| BBNX | BETA BIONICS INC | $13.3M | 1,324,000 | 0.16% | +41% |
Trimmed (9)
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| NBIX | NEUROCRINE BIOSCIENCES INC | $80.4M | 610,000 | 0.95% | -48% |
| IDYA | IDEAYA BIOSCIENCES INC | $51.0M | 1,530,008 | 0.60% | -29% |
| RVMD | REVOLUTION MEDICINES INC | $223.4M | 2,297,000 | 2.64% | -21% |
| CATALYST PHARMACEUTICALS | CATALYST PHARMACEUTICALS INC | $97.6M | 3,943,600 | 1.15% | -20% |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | $98.6M | 1,573,297 | 1.16% | -14% |
| VERA | VERA THERAPEUTICS INC | $149.7M | 3,722,100 | 1.77% | -8% |
| CNC | CENTENE CORP DEL | $193.7M | 5,917,091 | 2.29% | -8% |
| EMBC | EMBECTA CORP | $22.4M | 2,534,961 | 0.26% | -8% |
| NVST | ENVISTA HOLDINGS CORPORATION | $56.1M | 2,210,100 | 0.66% | -3% |
The book
All reported holdings
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| NUVALENT INC | NUVALENT INC | $1.8B | 17,248,450 | 20.85% | — |
| BKD 3.5 10/15/29 | BROOKDALE SR LIVING INC | $505.4M | 306,885,000 | 5.96% | — |
| COGT | COGENT BIOSCIENCES INC | $348.1M | 9,043,903 | 4.11% | — |
| PRAX | PRAXIS PRECISION MEDICINES I | $310.4M | 963,351 | 3.66% | — |
| VTRS | VIATRIS INC | $273.0M | 20,206,170 | 3.22% | — |
| UTHR | UNITED THERAPEUTICS CORP DEL | $271.0M | 457,000 | 3.20% | — |
| RVMD | REVOLUTION MEDICINES INC | $223.4M | 2,297,000 | 2.64% | — |
| MIRM 4 05/01/29 | MIRUM PHARMACEUTICALS INC | $209.4M | 70,000,000 | 2.47% | — |
| ARWR 0 01/15/32 | ARROWHEAD PHARMACEUTICALS IN | $207.2M | 200,000,000 | 2.44% | — |
| CELC | CELCUITY INC | $195.6M | 1,714,000 | 2.31% | — |
| CNC | CENTENE CORP DEL | $193.7M | 5,917,091 | 2.29% | — |
| LRMR | LARIMAR THERAPEUTICS INC | $160.2M | 35,606,974 | 1.89% | — |
| BKD | BROOKDALE SR LIVING INC | $159.2M | 11,637,032 | 1.88% | — |
| VERA | VERA THERAPEUTICS INC | $149.7M | 3,722,100 | 1.77% | — |
| IONS | IONIS PHARMACEUTICALS INC | $148.7M | 1,979,669 | 1.75% | — |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $143.2M | 15,038,000 | 1.69% | — |
| INSP | INSPIRE MED SYS INC | $139.4M | 2,703,238 | 1.64% | — |
| LEGN | LEGEND BIOTECH CORP | $139.1M | 7,687,638 | 1.64% | — |
| AHCO | ADAPTHEALTH CORP | $136.6M | 11,477,730 | 1.61% | — |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | $136.5M | 4,264,789 | 1.61% | — |
| ACHC | ACADIA HEALTHCARE COMPANY IN | $105.7M | 4,520,000 | 1.25% | — |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | $98.6M | 1,573,297 | 1.16% | — |
| CATALYST PHARMACEUTICALS | CATALYST PHARMACEUTICALS INC | $97.6M | 3,943,600 | 1.15% | — |
| INDV | INDIVIOR PHARMACEUTICALS INC | $94.4M | 3,097,790 | 1.11% | — |
| XENE | XENON PHARMACEUTICALS INC | $94.0M | 1,615,696 | 1.11% | — |
| IONS 1.75 06/15/28 | IONIS PHARMACEUTICALS INC | $90.6M | 60,000,000 | 1.07% | — |
| PHVS | PHARVARIS N V | $88.3M | 3,126,042 | 1.04% | — |
| SNDX | SYNDAX PHARMACEUTICALS INC | $88.3M | 3,779,900 | 1.04% | — |
| TNGX | TANGO THERAPEUTICS INC | $86.8M | 4,146,813 | 1.02% | — |
| ALHC 4.25 11/15/29 | ALIGNMENT HEALTHCARE INC | $85.9M | 61,000,000 | 1.01% | — |
| DNTH | DIANTHUS THERAPEUTICS INC | $85.6M | 1,019,813 | 1.01% | — |
| PFE | PFIZER INC | $85.4M | 3,040,000 | 1.01% | — |
| NBIX | NEUROCRINE BIOSCIENCES INC | $80.4M | 610,000 | 0.95% | — |
| DAWNGBX | DAY ONE BIOPHARMACEUTICALS I | $79.8M | 3,723,131 | 0.94% | — |
| SVRA | SAVARA INC | $74.1M | 13,569,000 | 0.87% | — |
| ZBIO 2.5 04/01/32 | ZENAS BIOPHARMA INC | $67.3M | 65,000,000 | 0.79% | — |
| ENHABIT INC | ENHABIT INC | $66.9M | 4,747,746 | 0.79% | — |
| NEO 0.25 01/15/28 | NEOGENOMICS INC | $66.7M | 72,689,000 | 0.79% | — |
| GMAB | GENMAB A/S | $66.1M | 2,462,000 | 0.78% | — |
| BIO | BIO RAD LABS INC | $63.0M | 226,070 | 0.74% | — |
| LNTH | LANTHEUS HLDGS INC | $62.8M | 827,999 | 0.74% | — |
| SPRY | ARS PHARMACEUTICALS INC | $60.3M | 7,503,812 | 0.71% | — |
| STOK | STOKE THERAPEUTICS INC | $59.4M | 1,823,500 | 0.70% | — |
| NVST | ENVISTA HOLDINGS CORPORATION | $56.1M | 2,210,100 | 0.66% | — |
| IDYA | IDEAYA BIOSCIENCES INC | $51.0M | 1,530,008 | 0.60% | — |
| BLTE | BELITE BIO INC | $48.5M | 304,013 | 0.57% | — |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $48.1M | 851,556 | 0.57% | — |
| KYMR | KYMERA THERAPEUTICS INC | $46.7M | 561,170 | 0.55% | — |
| CERT | CERTARA INC | $44.5M | 7,808,605 | 0.53% | — |
| BBOT | BRIDGEBIO ONCOLOGY THERAPEUT | $43.7M | 4,885,446 | 0.52% | — |
| IRON | DISC MEDICINE INC | $42.0M | 657,000 | 0.50% | — |
| LIVN 2.5 03/15/29 | LIVANOVA PLC | $40.0M | 34,280,000 | 0.47% | — |
| SION | SIONNA THERAPEUTICS INC | $38.9M | 970,590 | 0.46% | — |
| CDNA | CAREDX INC | $38.0M | 2,191,000 | 0.45% | — |
| GPCR | STRUCTURE THERAPEUTICS INC | $37.0M | 767,993 | 0.44% | — |
| IMCR 2.5 02/01/30 | IMMUNOCORE HLDGS PLC | $27.0M | 30,000,000 | 0.32% | — |
| VCYT | VERACYTE INC | $23.4M | 726,000 | 0.28% | — |
| ALNY | ALNYLAM PHARMACEUTICALS INC | $22.5M | 67,935 | 0.27% | — |
| EMBC | EMBECTA CORP | $22.4M | 2,534,961 | 0.26% | — |
| TYRA | TYRA BIOSCIENCES INC | $21.0M | 549,000 | 0.25% | — |
| FHTX | FOGHORN THERAPEUTICS INC | $21.0M | 4,394,367 | 0.25% | — |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | $20.7M | 283,000 | 0.24% | — |
| CMPX | COMPASS THERAPEUTICS INC | $19.1M | 3,606,000 | 0.23% | — |
| MNPR | MONOPAR THERAPEUTICS INC | $17.7M | 323,745 | 0.21% | — |
| KYTX | KYVERNA THERAPEUTICS INC | $17.3M | 2,000,000 | 0.20% | — |
| SGP | SPYGLASS PHARMA INC | $14.3M | 550,000 | 0.17% | — |
| BBNX | BETA BIONICS INC | $13.3M | 1,324,000 | 0.16% | — |
| TSHA | TAYSHA GENE THERAPIES INC | $12.2M | 2,722,165 | 0.14% | — |
| STLN | THE ONCOLOGY INSTITUTE INC | $10.3M | 3,360,052 | 0.12% | — |
| CGEM | CULLINAN THERAPEUTICS INC | $5.5M | 386,169 | 0.06% | — |
| ANNX | ANNEXON INC | $3.2M | 583,913 | 0.04% | — |
| ALEC | ALECTOR INC | $2.3M | 1,055,192 | 0.03% | — |
| NEWAMSTERDAM PHARMA COMP | NEWAMSTERDAM PHARMA COMPANY | $1.9M | 92,787 | 0.02% | — |
| EW | EDWARDS LIFESCIENCES CORP | $1.1M | 13,702 | 0.01% | — |
| PHGE | BIOMX INC | $492,795 | 131,272 | 0.01% | — |
| MANE | VERADERMICS INC | $315,750 | 5,000 | 0.00% | — |
| HUM | HUMANA INC | $158,999 | 917 | 0.00% | — |
| STLNW | THE ONCOLOGY INSTITUTE INC | $54,750 | 1,250,000 | 0.00% | — |
| QSIAW | QUANTUM SI INC | $36,200 | 333,333 | 0.00% | — |
| PMVP | PMV PHARMACEUTICALS INC | $10,900 | 8,790 | 0.00% | — |
| SURROZEN INC | SURROZEN INC | $2,667 | 166,666 | 0.00% | — |
| MYGN | MYRIAD GENETICS INC | $2,273 | 505 | 0.00% | — |
Rows are aggregated by CUSIP — a manager files the same security multiple times when different internal desks hold it. Tickers link to our own backtest of that asset where we cover it.
Read the original
This page was built from one document: the 2026-03-31 Form 13F info table filed by DEERFIELD MANAGEMENT COMPANY, L.P. (CIK 1009258, accession 0001213900-26-057678). Every other 13F site is reading the same file.
If anything here disagrees with it, the filing wins — and we would want to know. All 13F filings by this manager
What a 13F cannot show you
A 13F is a long-only equity snapshot, and the holes in it are structural. Anyone selling you this data as "what the smart money is doing" is selling you one leg of a position:
- No short positions. None, ever. A fund shown here as bullish may be net short the same name through a book you cannot see.
- No cash, bonds, FX, commodities or non-US listings. A macro fund's entire thesis can be invisible.
- No intra-quarter round trips. Bought and sold inside the same quarter means it never appears at all.
- Options are notional, not ownership. We keep puts and calls in a separate bucket rather than adding their notional into a fund's book size, which is how a $2B fund gets reported as a $20B one.
- Confidential treatment. Managers can ask the SEC to withhold a position while they build it. Those holdings are legally absent from the filing, so a "new" position may be months old.
Tested and published by IndicatorEdge · backtest grid generated 2026-06-25 · base rates recomputed 2026-07-31 · how we test
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