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The best indicator for Pfizer (PFE)

We backtested 382 indicators across daily, weekly and hourly charts on real Pfizer (PFE) history. Here's what actually worked — risk-adjusted over the full backtest, with costs, and checked out-of-sample.

Signaling LONG right now — SMC: Change of Character (Weekly) has been long for 58 bars. Signal as of 2026-10-26.
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Key levels · as of 2026-10-26

Where Pfizer (PFE) stands

29.79
last daily close (2026-10-26)
26.21
200-day simple moving average price 13.7% above
28.36
50-day simple moving average price 5.1% above
22.70–30.42
52-week range

Computed from our own daily OHLCV history, not quoted from a third party. Moving averages use closing prices; "52-week" is the last 252 trading sessions.

Smart Money · Weekly

SMC: Change of Character

On the weekly chart, this is the strongest risk-adjusted edge we found for Pfizer (PFE) over ~54.5 years — trailing buy-and-hold by 0.2% CAGR.

10.0%
CAGR
0.57
Sharpe
-44.2%
Max DD
60.0%
Win rate
10.46
Profit factor
-0.2%
vs Buy&Hold
Chart

Pfizer (PFE) on the weekly chart

The timeframe our backtest found best for this asset. The chart is live market data; the results above are hypothetical and historical.

Chart by TradingView. Loading it contacts tradingview.com, which may set its own cookies — see our privacy policy.

NOTHING BEAT BUY-AND-HOLD
Full strategy report — every setup ranked out-of-sample, corrected for data-mining, and forward-tracked in public.
Read the verdict
Confluence · Weekly

Best multi-indicator combo

EMA 20/50 CrossHull Suite

Going long only when all 2 agree was the strongest confluence setup we found for Pfizer (PFE) — trailing buy-and-hold by 4.6% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.

5.5%
CAGR
0.4
Sharpe
41.5%
Win rate
53
Trades
-4.6%
vs Buy&Hold
Best by timeframe

The winner on each chart

Weekly
SMC: Change of Character
-0.2% · Sharpe 0.57
Daily
Intraday Momentum Index
-2.3% · Sharpe 0.49
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1SMC: Change of Character ✓Weekly10.0%0.57-44.2%60.0%25-0.2%
2Volume Flow Indicator ✓Weekly9.9%0.56-47.6%58.8%17-0.3%
3Positive Volume Index ✓Weekly9.6%0.55-50.3%56.2%16-0.7%
4CCI (200) ✓Weekly9.7%0.55-54.1%40.0%25-0.6%
5Trend Intensity Index ✓Weekly9.3%0.54-51.6%62.5%16-1.0%
6Fibonacci Pivots ✓Weekly7.6%0.53-45.3%55.1%430-2.6%
7EMA 200 Trend ✓Weekly9.4%0.53-49.4%43.2%37-0.8%
8T3 10/40 Cross ✓Weekly8.5%0.53-52.2%53.8%26-1.7%
9SMA 200 Trend ✓Weekly8.9%0.52-48.0%44.0%25-1.4%
10SMA 20/80 Cross ✓Weekly8.6%0.52-49.3%57.9%19-1.6%
11T3 15/60 Cross ✓Weekly8.1%0.51-53.2%61.1%18-2.2%
12Pivot Points (Standard) ✓Weekly6.9%0.5-49.2%53.3%390-3.4%
13TRIMA 200 Trend ✓Weekly8.5%0.5-50.2%39.1%23-1.8%
14Intraday Momentum Index ✓Daily8.0%0.49-52.5%69.8%159-2.3%

✓ = held up out-of-sample. Hypothetical, costs included. See methodology.

The leverage question

What it would take to beat buy & hold on Pfizer (PFE)

2 of 719 tested setups beat buy-and-hold on Pfizer (PFE) outright. Another 144 could get there with leverage they would survive — but 412 would be liquidated by their own drawdown before they caught it.

IndicatorBeats B&H unlevered Leverage neededLeverage survived
Murrey Math Lines1none needed3.09×
Trade Volume Index1none needed1.74×
Volatility Stop (ATR)—1.39×2.69×
Bollinger Mean-Reversion—1.65×3.55×
Fibonacci Bands—1.65×3.55×
Order-Flow Reversion—1.69×4.33×

Out-of-sample, costs included. A setup is only listed if the leverage it needs is less than the leverage its own worst drawdown survives — when it isn't, no amount of leverage gets there. Volatility drag isn't modelled, so these are the optimistic case. Every indicator, ranked this way

What this means

For Pfizer (PFE), SMC: Change of Character on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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