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The best indicator for Pfizer (PFE)

We backtested 366 indicators across daily, weekly and hourly charts on real Pfizer (PFE) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Signaling FLAT right now — Fibonacci Pivots (Weekly) is out of the market, as of 2026-06-08.
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Mean Reversion · Weekly

Fibonacci Pivots

On the weekly chart, this is the strongest risk-adjusted edge we found for Pfizer (PFE) over ~54.2 years — trailing buy-and-hold by 1.8% CAGR.

8.3%
CAGR
0.56
Sharpe
-43.3%
Max DD
56.0%
Win rate
1.5
Profit factor
-1.8%
vs Buy&Hold
Confluence · Weekly

Best multi-indicator combo

EMA 20/50 CrossHull Suite

Going long only when all 2 agree was the strongest confluence setup we found for Pfizer (PFE) — trailing buy-and-hold by 4.6% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.

5.5%
CAGR
0.4
Sharpe
41.5%
Win rate
53
Trades
-4.6%
vs Buy&Hold
Best by timeframe

The winner on each chart

Weekly
Fibonacci Pivots
-1.8% · Sharpe 0.56
Daily
Intraday Momentum Index
-2.2% · Sharpe 0.49
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1Fibonacci Pivots Weekly8.3%0.56-43.3%56.0%432-1.8%
2CCI (200) Weekly9.7%0.55-53.6%39.1%23-0.4%
3Trend Intensity Index Weekly9.2%0.54-51.2%62.5%16-0.9%
4SMC: Change of Character Weekly9.3%0.54-44.2%52.0%25-0.8%
5Positive Volume Index Weekly8.8%0.52-56.0%65.0%20-1.3%
6EMA 200 Trend Weekly9.2%0.52-51.7%42.1%38-0.9%
7SMA 200 Trend Weekly9.0%0.52-48.0%45.8%24-1.1%
8T3 10/40 Cross Weekly8.3%0.52-52.1%53.8%26-1.7%
9Vegas Tunnel Weekly8.5%0.51-46.3%36.4%33-1.6%
10Pivot Points (Standard) Weekly7.0%0.51-48.2%55.2%388-3.1%
11SMA 20/80 Cross Weekly8.5%0.51-49.3%57.9%19-1.6%
12TRIMA 200 Trend Weekly8.4%0.5-50.9%39.1%23-1.7%
13T3 15/60 Cross Weekly7.8%0.5-53.2%61.1%18-2.2%
14Intraday Momentum Index Daily7.9%0.49-52.5%69.0%158-2.2%

= held up out-of-sample. Hypothetical, costs included. See methodology.

What this means

For Pfizer (PFE), Fibonacci Pivots on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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