The best indicator for Vertex Pharmaceuticals (VRTX)
We backtested 382 indicators across daily, weekly and hourly charts on real Vertex Pharmaceuticals (VRTX) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.
Projection Bands
On the weekly chart, this is the strongest risk-adjusted edge we found for Vertex Pharmaceuticals (VRTX) over ~35.0 years — beating buy-and-hold by 0.3% CAGR.
Best multi-indicator combo
Going long only when all 2 agree was the strongest confluence setup we found for Vertex Pharmaceuticals (VRTX) — trailing buy-and-hold by 5.9% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.
The winner on each chart
Every indicator, ranked
Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.
| # | Indicator | TF | CAGR | Sharpe | Max DD | Win | Trades | vs B&H |
|---|---|---|---|---|---|---|---|---|
| 1 | Projection Bands ✓ | Weekly | 14.4% | 0.58 | -70.4% | 75.7% | 70 | 0.3% |
| 2 | Stochastic Momentum Index ✓ | Weekly | 11.9% | 0.52 | -48.7% | 75.8% | 33 | -2.2% |
| 3 | MA Envelope ✓ | Weekly | 13.4% | 0.52 | -76.0% | 70.8% | 96 | -0.6% |
| 4 | Stochastic ✓ | Daily | 11.8% | 0.49 | -75.0% | 70.8% | 168 | -2.3% |
| 5 | QQE ✓ | Weekly | 13.4% | 0.49 | -93.1% | 47.6% | 103 | -0.6% |
| 6 | Williams %R ✓ | Weekly | 11.4% | 0.48 | -63.1% | 75.0% | 56 | -2.7% |
| 7 | Keltner Mean-Reversion ✓ | Weekly | 7.3% | 0.48 | -39.9% | 93.3% | 15 | -6.7% |
| 8 | SMC: Equal Highs / Lows ✓ | Daily | 12.4% | 0.48 | -67.7% | 64.7% | 17 | -1.7% |
| 9 | SMC: Change of Character ✓ | Weekly | 11.6% | 0.48 | -80.9% | 64.7% | 17 | -2.4% |
| 10 | ADXR ✓ | Daily | 10.4% | 0.47 | -73.9% | 46.7% | 246 | -3.7% |
| 11 | VWAP Bands ✓ | Weekly | 8.3% | 0.47 | -44.5% | 82.6% | 23 | -5.7% |
| 12 | McGinley 200 Trend ✓ | Daily | 11.2% | 0.46 | -94.0% | 28.0% | 25 | -2.9% |
| 13 | Stochastic ✓ | Weekly | 10.5% | 0.46 | -63.6% | 71.1% | 38 | -3.5% |
| 14 | WaveTrend (8/6/4) ✓ | Weekly | 10.5% | 0.46 | -71.0% | 71.9% | 32 | -3.5% |
✓ = held up out-of-sample. Hypothetical, costs included. See methodology.
For Vertex Pharmaceuticals (VRTX), Projection Bands on the weekly timeframe gave the best balance of return and risk in our test. It beat buy-and-hold — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.
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