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The best indicator for Merck & Co. (MRK)

We backtested 382 indicators across daily, weekly and hourly charts on real Merck & Co. (MRK) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.

Signaling LONG right now — Supertrend (14,4) (Weekly) has been long for 43 bars. Signal computed on 2026-09-07, 2 days behind the price data on this page (it is rebuilt on a separate schedule).
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Key levels · as of 2026-09-09

Where Merck & Co. (MRK) stands

147.53
last daily close (2026-09-09)
117.99
200-day simple moving average price 25.0% above
135.35
50-day simple moving average price 9.0% above
75.83–156.45
52-week range

Computed from our own daily OHLCV history, not quoted from a third party. Moving averages use closing prices; "52-week" is the last 252 trading sessions.

Trend · Weekly

Supertrend (14,4)

On the weekly chart, this is the strongest risk-adjusted edge we found for Merck & Co. (MRK) over ~64.7 years — trailing buy-and-hold by 2.2% CAGR.

10.3%
CAGR
0.64
Sharpe
-44.0%
Max DD
73.9%
Win rate
18.91
Profit factor
-2.2%
vs Buy&Hold
Chart

Merck & Co. (MRK) on the weekly chart

The timeframe our backtest found best for this asset. The chart is live market data; the results above are hypothetical and historical.

Chart by TradingView. Loading it contacts tradingview.com, which may set its own cookies — see our privacy policy.

NOTHING BEAT BUY-AND-HOLD
Full strategy report — every setup ranked out-of-sample, corrected for data-mining, and forward-tracked in public.
Read the verdict
Confluence · Weekly

Best multi-indicator combo

EMA 20/50 CrossQQE

Going long only when all 2 agree was the strongest confluence setup we found for Merck & Co. (MRK) — trailing buy-and-hold by 2.9% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.

9.6%
CAGR
0.58
Sharpe
52.0%
Win rate
173
Trades
-2.9%
vs Buy&Hold
Best by timeframe

The winner on each chart

Weekly
Supertrend (14,4)
-2.2% · Sharpe 0.64
Daily
EMA 50/200 Cross
-2.0% · Sharpe 0.62
Full results

Every indicator, ranked

Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.

#IndicatorTFCAGRSharpeMax DDWinTradesvs B&H
1Supertrend (14,4) Weekly10.3%0.64-44.0%73.9%23-2.2%
2TRIX (21) Weekly10.8%0.63-49.8%65.2%23-1.7%
3EMA 50/200 Cross Daily10.5%0.62-57.4%50.0%38-2.0%
4CCI (200) Daily9.9%0.62-58.7%28.8%191-2.5%
5Awesome Oscillator Weekly10.4%0.62-54.6%50.0%58-2.2%
6TRIX (9) Weekly10.4%0.62-49.0%53.6%56-2.2%
7EMA 10/40 Cross Weekly10.6%0.62-62.3%53.8%39-1.9%
8TRIX (15) Weekly10.5%0.62-42.9%63.3%30-2.0%
9SMA 50/200 Cross Daily10.0%0.61-56.4%56.4%39-2.4%
10EMA 20/50 Cross Weekly10.6%0.61-45.9%65.2%23-1.9%
11SMA 10/40 Cross Weekly10.3%0.61-51.4%52.6%38-2.2%
12WMA 10/40 Cross Weekly10.1%0.61-51.6%52.6%57-2.5%
13WMA 15/60 Cross Weekly10.4%0.61-54.4%60.0%40-2.2%
14T3 10/40 Cross Weekly9.8%0.61-46.2%63.9%36-2.7%

= held up out-of-sample. Hypothetical, costs included. See methodology.

The leverage question

What it would take to beat buy & hold on Merck & Co. (MRK)

3 of 731 tested setups beat buy-and-hold on Merck & Co. (MRK) outright. Another 171 could get there with leverage they would survive — but 257 would be liquidated by their own drawdown before they caught it.

IndicatorBeats B&H unlevered Leverage neededLeverage survived
Intraday Momentum Index1none needed2.47×
T3 10/40 Cross1none needed2.79×
Predictive Ranges1none needed2.91×
EMA 200 Trend1.39×2.38×
VIDYA 30 Trend1.4×2.64×
CCI (200)1.41×2.47×

Out-of-sample, costs included. A setup is only listed if the leverage it needs is less than the leverage its own worst drawdown survives — when it isn't, no amount of leverage gets there. Volatility drag isn't modelled, so these are the optimistic case. Every indicator, ranked this way

What this means

For Merck & Co. (MRK), Supertrend (14,4) on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.

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