The best indicator for Merck & Co. (MRK)
We backtested 366 indicators across daily, weekly and hourly charts on real Merck & Co. (MRK) history. Here's what actually worked — risk-adjusted, out-of-sample, with costs.
Supertrend (14,4)
On the weekly chart, this is the strongest risk-adjusted edge we found for Merck & Co. (MRK) over ~64.7 years — trailing buy-and-hold by 2.2% CAGR.
Best multi-indicator combo
Going long only when all 2 agree was the strongest confluence setup we found for Merck & Co. (MRK) — trailing buy-and-hold by 2.9% CAGR, out-of-sample. Fewer, higher-conviction trades than any single indicator.
The winner on each chart
Every indicator, ranked
Ranked by Sharpe (risk-adjusted return). Hypothetical, fees included.
| # | Indicator | TF | CAGR | Sharpe | Max DD | Win | Trades | vs B&H |
|---|---|---|---|---|---|---|---|---|
| 1 | Supertrend (14,4) ✓ | Weekly | 10.3% | 0.64 | -44.0% | 73.9% | 23 | -2.2% |
| 2 | TRIX (21) ✓ | Weekly | 10.8% | 0.63 | -49.8% | 65.2% | 23 | -1.7% |
| 3 | EMA 50/200 Cross ✓ | Daily | 10.5% | 0.62 | -57.4% | 50.0% | 38 | -2.0% |
| 4 | CCI (200) ✓ | Daily | 9.9% | 0.62 | -58.7% | 28.8% | 191 | -2.5% |
| 5 | Awesome Oscillator ✓ | Weekly | 10.4% | 0.62 | -54.6% | 50.0% | 58 | -2.2% |
| 6 | TRIX (9) ✓ | Weekly | 10.4% | 0.62 | -49.0% | 53.6% | 56 | -2.2% |
| 7 | EMA 10/40 Cross ✓ | Weekly | 10.6% | 0.62 | -62.3% | 53.8% | 39 | -1.9% |
| 8 | TRIX (15) ✓ | Weekly | 10.5% | 0.62 | -42.9% | 63.3% | 30 | -2.0% |
| 9 | SMA 50/200 Cross ✓ | Daily | 10.0% | 0.61 | -56.4% | 56.4% | 39 | -2.4% |
| 10 | EMA 20/50 Cross ✓ | Weekly | 10.6% | 0.61 | -45.9% | 65.2% | 23 | -1.9% |
| 11 | SMA 10/40 Cross ✓ | Weekly | 10.3% | 0.61 | -51.4% | 52.6% | 38 | -2.2% |
| 12 | WMA 10/40 Cross ✓ | Weekly | 10.1% | 0.61 | -51.6% | 52.6% | 57 | -2.5% |
| 13 | WMA 15/60 Cross ✓ | Weekly | 10.4% | 0.61 | -54.4% | 60.0% | 40 | -2.2% |
| 14 | T3 10/40 Cross ✓ | Weekly | 9.8% | 0.61 | -46.2% | 63.9% | 36 | -2.7% |
✓ = held up out-of-sample. Hypothetical, costs included. See methodology.
For Merck & Co. (MRK), Supertrend (14,4) on the weekly timeframe gave the best balance of return and risk in our test. It still trailed buy-and-hold on raw return — but remember: this is a hypothetical backtest of a standard rule, not a recommendation. Markets change. See the methodology and disclaimer.
More stock
Get the weekly edge report
The best-performing indicator per asset, what changed this week, and the honest caveats — straight to your inbox.