13F holdings
RA CAPITAL MANAGEMENT, L.P. portfolio
Managed by . 85 reported positions worth $9.4B as of 2026-03-31, filed with the SEC on 2026-05-15. Parsed from the filing itself, not a reseller.
$9.4B
Book value
85
Positions
61%
Top 10 weight
+24
New this quarter
-10
Exited
134 days
Age today
How old this actually is
Every position on this page is a snapshot of 2026-03-31. It was already 45 days old on 2026-05-15, the day it first became public. Today it is 134 days old.
That lag is the law, not a service level — Rule 13f-1 gives managers 45 days after quarter end to file, and no product can shorten it. A fund can have sold every share below before you read this sentence. Treat it as a record of what happened, never as a position you can follow.
What changed
Positions opened and closed
Against its 2025-12-31 filing. This is the part worth reading — the holdings table below is mostly years old.
New positions (24)
| Ticker | Issuer | Value | Shares | % of book |
|---|---|---|---|---|
| SGP | SPYGLASS PHARMA INC | $207.8M | 8,021,117 | 2.20% |
| ZLAB | ZAI LAB LTD-ADR | $107.4M | 5,707,262 | 1.14% |
| SRPT | SAREPTA THERAPEUTICS INC | $84.9M | 3,902,596 | 0.90% |
| DAMORA THERAPEUTICS INC | DAMORA THERAPEUTICS INC | $62.1M | 2,399,310 | 0.66% |
| XNCR | XENCOR INC | $59.1M | 4,897,237 | 0.63% |
| IPSC | CENTURY THERAPEUTICS INC | $40.1M | 17,754,430 | 0.43% |
| MIRM | MIRUM PHARMACEUTICALS INC | $29.4M | 318,554 | 0.31% |
| BIOA | BIOAGE LABS INC | $28.9M | 1,650,648 | 0.31% |
| AKTS | AKTIS ONCOLOGY INC | $26.9M | 1,503,084 | 0.28% |
| ALXO | ALX ONCOLOGY HOLDINGS INC | $26.1M | 13,011,849 | 0.28% |
| ACRS | ACLARIS THERAPEUTICS INC | $25.5M | 6,804,072 | 0.27% |
| TVTX | TRAVERE THERAPEUTICS INC | $22.2M | 746,841 | 0.24% |
| RLMD | RELMADA THERAPEUTICS INC | $20.5M | 2,947,369 | 0.22% |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | $19.3M | 265,000 | 0.20% |
| STRO | SUTRO BIOPHARMA INC | $17.8M | 715,307 | 0.19% |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | $16.6M | 3,000,000 | 0.18% |
| OKUR | ONKURE THERAPEUTICS INC-A | $16.6M | 3,998,333 | 0.18% |
| HLXC | HELIX ACQUISITION CORP-CL A | $12.7M | 1,250,000 | 0.13% |
| RNA | ATRIUM THERAPEUTICS INC | $11.6M | 864,102 | 0.12% |
| KPTI | KARYOPHARM THERAPEUTICS INC | $10.7M | 1,917,354 | 0.11% |
| CRVS | CORVUS PHARMACEUTICALS INC | $6.6M | 450,000 | 0.07% |
| EQ | EQUILLIUM INC | $6.2M | 3,096,336 | 0.07% |
| MGNX | MACROGENICS INC | $5.4M | 1,864,176 | 0.06% |
| MPLT | MAPLIGHT THERAPEUTICS INC | $5.0M | 248,294 | 0.05% |
Closed out (10)
| Ticker | Issuer | Was worth | Shares | % of book |
|---|---|---|---|---|
| CDTX | CIDARA THERAPEUTICS INC | $743.4M | 3,365,523 | 0.00% |
| RNAGBP | AVIDITY BIOSCIENCES INC | $623.3M | 8,641,031 | 0.00% |
| ACLXGBX | ARCELLX INC | $82.6M | 1,267,156 | 0.00% |
| BLTE | BELITE BIO INC - ADR | $69.2M | 432,484 | 0.00% |
| IVVD | INVIVYD INC | $42.3M | 17,119,096 | 0.00% |
| MDLN | MEDLINE INC-CL A | $14.1M | 335,000 | 0.00% |
| PGNY | PROGYNY INC | $2.5M | 96,628 | 0.00% |
| QGEN | QIAGEN N.V. | $2.1M | 43,976 | 0.00% |
| KIDS | ORTHOPEDIATRICS CORP | $2.0M | 109,959 | 0.00% |
| HCAT | HEALTH CATALYST INC | $1.9M | 793,749 | 0.00% |
Added to (16)
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| PCVX | VAXCYTE INC | $666.8M | 11,474,599 | 7.07% | +7% |
| NUVALENT INC-A | NUVALENT INC-A | $259.6M | 2,534,145 | 2.75% | +35% |
| DNTH | DIANTHUS THERAPEUTICS INC | $219.2M | 2,611,733 | 2.32% | +62% |
| MLYS | MINERALYS THERAPEUTICS INC | $208.4M | 7,692,750 | 2.21% | +5% |
| 1U5 | WAVE LIFE SCIENCES LTD | $195.6M | 26,975,505 | 2.07% | +48% |
| IRON | DISC MEDICINE INC | $156.7M | 2,450,221 | 1.66% | +24% |
| BCAX | BICARA THERAPEUTICS INC | $144.3M | 7,255,993 | 1.53% | +4% |
| EVMN | EVOMMUNE INC | $80.3M | 3,494,638 | 0.85% | +1% |
| SLDB | SOLID BIOSCIENCES INC | $67.2M | 9,339,978 | 0.71% | +61% |
| ABOS | ACUMEN PHARMACEUTICALS INC | $49.5M | 20,992,669 | 0.52% | +41% |
| DSGN | DESIGN THERAPEUTICS INC | $31.6M | 2,972,973 | 0.34% | +103% |
| INSP | INSPIRE MEDICAL SYSTEMS INC | $16.8M | 325,663 | 0.18% | +129% |
| HNGE | HINGE HEALTH INC-A | $14.1M | 364,613 | 0.15% | +355% |
| WGS | GENEDX HOLDINGS CORP | $13.5M | 209,887 | 0.14% | +262% |
| WAY | WAYSTAR HOLDING CORP | $12.8M | 529,400 | 0.14% | +267% |
Trimmed (2)
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| CTNM | CONTINEUM THERAPEUTICS INC-A | $16.9M | 1,296,012 | 0.18% | -41% |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | $47.0M | 5,049,779 | 0.50% | -11% |
The book
All reported holdings
| Ticker | Issuer | Value | Shares | % of book | Shares Δ |
|---|---|---|---|---|---|
| ASCENDIS PHARMA A/S - AD | ASCENDIS PHARMA A/S - ADR | $2.4B | 10,281,496 | 24.92% | — |
| PCVX | VAXCYTE INC | $666.8M | 11,474,599 | 7.07% | — |
| RYTM | RHYTHM PHARMACEUTICALS INC | $579.8M | 6,666,837 | 6.14% | — |
| TYRA | TYRA BIOSCIENCES INC | $467.2M | 12,198,625 | 4.95% | — |
| SION | SIONNA THERAPEUTICS INC | $397.1M | 9,905,045 | 4.21% | — |
| EWTX | EDGEWISE THERAPEUTICS INC | $328.5M | 10,428,437 | 3.48% | — |
| NAMS | NEWAMSTERDAM PHARMA CO NV | $305.7M | 9,550,191 | 3.24% | — |
| NUVALENT INC-A | NUVALENT INC-A | $259.6M | 2,534,145 | 2.75% | — |
| DNTH | DIANTHUS THERAPEUTICS INC | $219.2M | 2,611,733 | 2.32% | — |
| MLYS | MINERALYS THERAPEUTICS INC | $208.4M | 7,692,750 | 2.21% | — |
| SGP | SPYGLASS PHARMA INC | $207.8M | 8,021,117 | 2.20% | — |
| 1U5 | WAVE LIFE SCIENCES LTD | $195.6M | 26,975,505 | 2.07% | — |
| SEPN | SEPTERNA INC | $168.1M | 6,995,858 | 1.78% | — |
| IRON | DISC MEDICINE INC | $156.7M | 2,450,221 | 1.66% | — |
| JANX | JANUX THERAPEUTICS INC | $155.5M | 11,189,693 | 1.65% | — |
| BCRX | BIOCRYST PHARMACEUTICALS INC | $150.7M | 15,827,186 | 1.60% | — |
| BCAX | BICARA THERAPEUTICS INC | $144.3M | 7,255,993 | 1.53% | — |
| PRAX | PRAXIS PRECISION MEDICINES I | $120.4M | 373,787 | 1.28% | — |
| GHRS | GH RESEARCH PLC | $107.9M | 7,676,697 | 1.14% | — |
| ZLAB | ZAI LAB LTD-ADR | $107.4M | 5,707,262 | 1.14% | — |
| TSHA | TAYSHA GENE THERAPIES INC | $105.3M | 23,555,648 | 1.12% | — |
| VOR | VOR BIOPHARMA INC | $96.4M | 5,404,998 | 1.02% | — |
| GERN | GERON CORP | $95.0M | 63,771,366 | 1.01% | — |
| SPRY | ARS PHARMACEUTICALS INC | $87.2M | 10,860,977 | 0.92% | — |
| SRPT | SAREPTA THERAPEUTICS INC | $84.9M | 3,902,596 | 0.90% | — |
| SYRE | SPYRE THERAPEUTICS INC | $81.8M | 1,621,620 | 0.87% | — |
| EVMN | EVOMMUNE INC | $80.3M | 3,494,638 | 0.85% | — |
| CLYM | CLIMB BIO INC | $77.4M | 11,300,939 | 0.82% | — |
| SLDB | SOLID BIOSCIENCES INC | $67.2M | 9,339,978 | 0.71% | — |
| ARTV | ARTIVA BIOTHERAPEUTICS INC | $63.5M | 9,853,302 | 0.67% | — |
| DAMORA THERAPEUTICS INC | DAMORA THERAPEUTICS INC | $62.1M | 2,399,310 | 0.66% | — |
| XNCR | XENCOR INC | $59.1M | 4,897,237 | 0.63% | — |
| LBRX | LB PHARMACEUTICALS INC | $54.5M | 2,208,604 | 0.58% | — |
| JBIO | JADE BIOSCIENCES INC | $51.6M | 3,671,083 | 0.55% | — |
| ABOS | ACUMEN PHARMACEUTICALS INC | $49.5M | 20,992,669 | 0.52% | — |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | $47.0M | 5,049,779 | 0.50% | — |
| FULC | FULCRUM THERAPEUTICS INC | $46.4M | 6,053,960 | 0.49% | — |
| CAPR | CAPRICOR THERAPEUTICS INC | $45.8M | 1,507,844 | 0.49% | — |
| IPSC | CENTURY THERAPEUTICS INC | $40.1M | 17,754,430 | 0.43% | — |
| OLMA | OLEMA PHARMACEUTICALS INC | $38.8M | 2,600,000 | 0.41% | — |
| LENZ | LENZ THERAPEUTICS INC | $38.2M | 4,178,823 | 0.41% | — |
| MNPR | MONOPAR THERAPEUTICS INC | $36.6M | 667,207 | 0.39% | — |
| PEPG | PEPGEN INC | $35.5M | 20,064,545 | 0.38% | — |
| DSGN | DESIGN THERAPEUTICS INC | $31.6M | 2,972,973 | 0.34% | — |
| MIRM | MIRUM PHARMACEUTICALS INC | $29.4M | 318,554 | 0.31% | — |
| BIOA | BIOAGE LABS INC | $28.9M | 1,650,648 | 0.31% | — |
| LXEO | LEXEO THERAPEUTICS INC | $28.7M | 5,000,000 | 0.30% | — |
| ASMB | ASSEMBLY BIOSCIENCES INC | $28.3M | 1,020,410 | 0.30% | — |
| RZLT | REZOLUTE INC | $28.0M | 9,180,000 | 0.30% | — |
| AKTS | AKTIS ONCOLOGY INC | $26.9M | 1,503,084 | 0.28% | — |
| ALXO | ALX ONCOLOGY HOLDINGS INC | $26.1M | 13,011,849 | 0.28% | — |
| ACRS | ACLARIS THERAPEUTICS INC | $25.5M | 6,804,072 | 0.27% | — |
| OVID | OVID THERAPEUTICS INC | $23.8M | 10,714,000 | 0.25% | — |
| NKTX | NKARTA INC | $22.8M | 10,805,129 | 0.24% | — |
| TVTX | TRAVERE THERAPEUTICS INC | $22.2M | 746,841 | 0.24% | — |
| GRAL | GRAIL INC | $22.1M | 428,266 | 0.23% | — |
| CCCC | C4 THERAPEUTICS INC | $21.0M | 8,000,000 | 0.22% | — |
| RLMD | RELMADA THERAPEUTICS INC | $20.5M | 2,947,369 | 0.22% | — |
| BNTC | BENITEC BIOPHARMA INC | $19.7M | 1,850,000 | 0.21% | — |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | $19.3M | 265,000 | 0.20% | — |
| STRO | SUTRO BIOPHARMA INC | $17.8M | 715,307 | 0.19% | — |
| CTNM | CONTINEUM THERAPEUTICS INC-A | $16.9M | 1,296,012 | 0.18% | — |
| SABS | SAB BIOTHERAPEUTICS INC | $16.9M | 4,401,500 | 0.18% | — |
| INSP | INSPIRE MEDICAL SYSTEMS INC | $16.8M | 325,663 | 0.18% | — |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | $16.6M | 3,000,000 | 0.18% | — |
| OKUR | ONKURE THERAPEUTICS INC-A | $16.6M | 3,998,333 | 0.18% | — |
| HNGE | HINGE HEALTH INC-A | $14.1M | 364,613 | 0.15% | — |
| WGS | GENEDX HOLDINGS CORP | $13.5M | 209,887 | 0.14% | — |
| WAY | WAYSTAR HOLDING CORP | $12.8M | 529,400 | 0.14% | — |
| HLXC | HELIX ACQUISITION CORP-CL A | $12.7M | 1,250,000 | 0.13% | — |
| PALI | PALISADE BIO INC | $12.5M | 7,124,116 | 0.13% | — |
| ACRV | ACRIVON THERAPEUTICS INC | $11.6M | 8,340,508 | 0.12% | — |
| RNA | ATRIUM THERAPEUTICS INC | $11.6M | 864,102 | 0.12% | — |
| KPTI | KARYOPHARM THERAPEUTICS INC | $10.7M | 1,917,354 | 0.11% | — |
| AVTX | AVALO THERAPEUTICS INC | $9.9M | 662,968 | 0.10% | — |
| FRNM | PERCEPTIVE CAPITAL SOLUTIONS | $8.2M | 750,000 | 0.09% | — |
| ACET | ADICET BIO INC | $8.1M | 1,182,624 | 0.09% | — |
| NEWAMSTERDAM PHARMA CO N | NEWAMSTERDAM PHARMA CO NV-27 | $6.7M | 333,333 | 0.07% | — |
| CRVS | CORVUS PHARMACEUTICALS INC | $6.6M | 450,000 | 0.07% | — |
| RANI | RANI THERAPEUTICS HOLDINGS-A | $6.2M | 8,500,000 | 0.07% | — |
| EQ | EQUILLIUM INC | $6.2M | 3,096,336 | 0.07% | — |
| HOWL | WEREWOLF THERAPEUTICS INC | $5.6M | 6,681,307 | 0.06% | — |
| MGNX | MACROGENICS INC | $5.4M | 1,864,176 | 0.06% | — |
| MPLT | MAPLIGHT THERAPEUTICS INC | $5.0M | 248,294 | 0.05% | — |
| PTN | PALATIN TECHNOLOGIES INC | $1.2M | 70,000 | 0.01% | — |
Rows are aggregated by CUSIP — a manager files the same security multiple times when different internal desks hold it. Tickers link to our own backtest of that asset where we cover it.
Read the original
This page was built from one document: the 2026-03-31 Form 13F info table filed by RA CAPITAL MANAGEMENT, L.P. (CIK 1346824, accession 0001104659-26-062637). Every other 13F site is reading the same file.
If anything here disagrees with it, the filing wins — and we would want to know. All 13F filings by this manager
What a 13F cannot show you
A 13F is a long-only equity snapshot, and the holes in it are structural. Anyone selling you this data as "what the smart money is doing" is selling you one leg of a position:
- No short positions. None, ever. A fund shown here as bullish may be net short the same name through a book you cannot see.
- No cash, bonds, FX, commodities or non-US listings. A macro fund's entire thesis can be invisible.
- No intra-quarter round trips. Bought and sold inside the same quarter means it never appears at all.
- Options are notional, not ownership. We keep puts and calls in a separate bucket rather than adding their notional into a fund's book size, which is how a $2B fund gets reported as a $20B one.
- Confidential treatment. Managers can ask the SEC to withhold a position while they build it. Those holdings are legally absent from the filing, so a "new" position may be months old.
Tested and published by IndicatorEdge · backtest grid generated 2026-06-25 · base rates recomputed 2026-07-31 · how we test
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